On Saturday, Real Madrid fell to Villarreal 2-1 and missed the opportunity to retake the league lead.
With a goal and an assist, Gerard Moreno led the Yellow Submarines to a decisive victory over the champs.
Karim Benzema’s effort from the penalty spot ultimately served as little more than solace.
Due to Madrid’s loss, Barcelona, the current title favorites, now has a chance to gain ground.
Barca and Real are tied for second position with 38 points each after Sunday’s away game against Atletico Madrid in fourth place.
With their third straight league victory, Villarreal climbs to fifth place.